Background and Purpose: A plethora of studies have been conducted in the past, which have proven the salutary effects of yoga practice. Yoga and other mind body techniques are deemed as stress relievers and have shown therapeutic effectiveness in preventing the development and progression of several lifestyle diseases including Diabetes. Yoga practice may help in managing Diabetes by regulating the glucose levels in blood. In this study we have evaluated the efficacy of three months of AYUSH-approved Diabetic Yoga Protocol (DYP) on high-risk individuals. Methods: Thirty three high-risk female participants with Indian Diabetes Risk Score (IDRS) ≥60 was recruited for a period of three months. The participants were divided into Diabetic Yoga Protocol Group (N = 18) and Control Group (N = 15). Alteration for selected glycemic, psychological, and anthropometric parameter of individuals was examined at the baseline and after three months of Yoga practices. Results: The three months of Yoga practice demonstrated significant changes on the levels of HbA1c (p = 0.010), Body Mass Index (BMI) (p = 0.006), sustained attention (p = 0.012), general health (p = 0.002), state anxiety (p = 0.001), perceived stress (p = 0.004), IDRS (p<0.001) and overall Quality of life (p<0.001). However, no significant changes were seen for Fasting Blood Sugar (FBS), and Waist Hip Ratio (WHR). While, in the control group, IDRS (p = 0.019) was significantly increased, significant decrease in BMI (p = 0.011) and state anxiety (p = 0.016) was observed. However, no significant changes were seen in HbA1c, FBS, WHR, Sustained Attention, General Health, Perceived Stress and Overall QOL. Conclusion: The findings of the present study are suggestive of DYP as a possible application for public health intervention regime for women.

A case of a 16-year-old Indian adolescent with discal herniation in L4 – L5 region with classical sign of ‘foot drop’ was successfully managed by conservative, non-surgical approach following principles of yoga intervention. Patients practised yoga under supervision of yoga expert, four times a day for first two weeks followed by once a day for consecutive two years. Yoga protocol included gentle yoga based loosening practices, simple asanas, yogic breathing techniques and yogic guided relaxation, pranayama and meditation. One year and two-year follow-ups showed complete revival of normal function and healing of the affected spinal cord disorder. A case which was recommended for surgery recovered with yoga intervention.

A 45-year-old male patient presented with bilateral solid renal mass probably renal cell carcinoma (RCC). After initial treatment, the patient got symptomatic relief from pain in flanks, acute retention of urine and hematuria. The patient initially declined repeated investigations but agreed for an ultrasound after two years of treatment; the result showed reduction in size of the mass. The urea, creatinine and hemoglobin percentage were normal and reported a normal blood pressure. The quality of life was maintained without the conventional surgery, radiotherapy, chemotherapy, or immunotherapy. While this case provides evidence of positive outcomes for homeopathic therapy, more studies are required in a hospital setting to establish the real extent to which this therapy may be employed.

This is a case study for invasive ductal carcinoma diagnosed in a patient aged 60 years in 2015. She went through chemotherapy and radiotherapy and was on remission in 2016. Bone density degeneration was the side effect from the breast cancer treatment. After trying the conventional treatment, she was not satisfied, she came to Union Yoga Ayurveda (UYA), Singapore. She came to clinic looking for alternative therapy to help her increase her bone density, cope up with weakness and overall mental and physical wellbeing. The patient was given holistic treatment of yoga and Ayurveda, involving patra pinda sweda (herbal compress) and picchu (herbal soaked gauze pieces). The yoga therapy involved asanas practise to increase strength, breathing and meditation for overall wellbeing. The patient was not on any other treatment/medication during the entire treatment. After uninterrupted therapy for six months there was an increase in her bone density along with increase in energy level. The patient case study is an attempt to provide yoga and Ayurveda as an alternative/supportive treatment for remission management osteoporosis from breast cancer patients.

A case of a 43 years old female with uterine fibroid and ovarian cyst was managed by an alternative, Non-surgical approach of yoga intervention. Yoga was practised under supervision daily twice a day for three months showed significant recovery from ovarian Cyst and reduction in uterine fibroid size. A diagnosis, where surgery was suggested as the only option, yoga has been found to be effective treatment modality in prevention and management.

This is a qualitative single subject intervention assessment involving the treatment of a 58 year old man, diagnosed with para-vertebral abscess due to tubercular pott's spine with Diabetes since 2008, administered with neuro anaesthesia for pain management, which could not succeed in providing complete relief and hence a parallel attempt was made to treat the same through an integrative mind-body approach to resolving pain. Basic challenges in this process were to conceptualize a personalized approach based on the constitution and personality of the seeker and selection of specific tools of yoga therapy to suit the individual's requirement. Adoption of yoga therapy involving synergized techniques resulted in holistic cure in a significantly reduced time interval. However, more studies are required to be adopted in the same manner to strengthen the line of the efficacy of such therapies in similar cases.

Background: The entire world is struggling from the COVID-19 pandemics. Scientific community all around the world have been looking for any possible measure to fight against this dreadful disease. Ayurveda, the traditional Indian system of medicine, has immense potential to contribute towards this pandemic both in prevention and management. But Ayurveda fraternity has the challenge to explain the available possible measures in contemporary language. The science of bioinformatics & epigenetics has provided possibility for scientific & contemporary explanation of Ayurvedic interventions. Summary: This paper is an attempt to discuss about various possibilities and challenges from Ayurveda perspective against COVID-19 in the purview of Ayurinformatics and Epigenetics. Key messages: Ayurinformatics have been applied successfully earlier to infectious diseases & scientists have screened many phytochemicals from medicinal plants in silico against covid 19. Further with the advance knowledge of epigenetics, intervention of Ayurveda on different expressed variants of coronavirus with intervention of screened phytochemicals discovered in silico with the knowledge of science of ayurinformatics will certainly contribute towards the fight with covid 19.