Integrative Medicine Case Reports

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Volume 5, Number 1, January 2024
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EDITORIAL

Reshma P. Jogdand

Evidence-based colors of universe as a alternative therapy in naturopathy

[Year:2024] [Month:January] [Volume:5] [Number:1] [Pages:2] [Pages No:1 - 2]

Keywords: Color Therapy, Cognition

   DOI: 10.38205/imcr.050101  |  Open Access |  How to cite  | 

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COMMENTARY

Aruna Rakha

Yogic Exercises as an Ergonomic Approach to Set Stem Cells in Motion

[Year:2024] [Month:January] [Volume:5] [Number:1] [Pages:2] [Pages No:3 - 4]

Keywords: Yoga, Stem Cells, Hypoxia

   DOI: 10.38205/imcr.050103  |  Open Access |  How to cite  | 

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RESEARCH ARTICLE

N. Ramya, B.S. Naveen, B. Geethakumari

A Randomized, Open-Label, Controlled Clinical Study to Evaluate the Efficacy of Guduchi Pindi in the Management of Anjananamika

[Year:2024] [Month:January] [Volume:5] [Number:1] [Pages:9] [Pages No:5 - 13]

Keywords: Anjananamika, Guduchi Pindi, Nimba Lodhra Pindi, Eyelid swelling, Stye, Chalazion

   DOI: 10.38205/imcr.050105  |  Open Access |  How to cite  | 

Abstract

Background: Anjananamika is one of the Vartmagata, Raktapradhana, Sadhya Netra Vikaras. These symptoms resemble nodular swelling on the eyelid. A stye, also known as hordeolum, is a common condition of the eye seen in ophthalmology and general medicine OPDs. Classically, a hordeolum usually appears as a little pustule on the edge of the eyelid. One of the most prevalent forms of eyelid lesions observed in the ophthalmology clinic is chalazion. It is a long-lasting, lipogranulomatous inflammatory lesion brought on by the Meibomian gland obstruction. Management of Anjananamika in Ayurveda classics consists of Swedana, Bhedana and Pratisarana. Although Pindi is not mentioned directly in the treatment modality of Anjananamika, Pindi can be taken as a form of Swedana. It works by absorbing substances through the transdermal route. Since the appendages are not notably present over the eye lid skin, the thinner stratum corneum of the eye lid skin indicates lower resistance, which may be the cause of higher drug absorption through the eye lid skin. The majority of absorption happens through the skin. Method: Study type is a Randomized comparative clinical study, the timing was prospective. Masking was open label, and grouping was double arm. Randomization was done by lottery method and group intervention method was parallel. The nature of Subjects presenting with the classical features of Anjananamika as described under diagnostic criteria. Subjects between the ages of 21 and 60, regardless of gender, occupation, religion, socioeconomic back-ground, or duration of illness. Subjects willing to participate with written informed consent, which is conveyed in the language which the subject can understand. Result: 40 patients registered for the study were randomly allocated to two groups A and B with 20 patients each. Within the group anal-ysis shows that both the groups have highly significant results i.e., progressive decrease in symptoms. The comparative analysis between the groups showed no significant results except for Kandu (p = 0.047). Yuvraj Sutar, Ajitkumar S Herwade, Late Kedari Redekar. To study efficacy of Rasanjantrikatu lepa on Anjannamika with special reference to Hordeolum externum. Total 60 patients were selected for study. Two groups, 30 patients in each group having Lakshanas of Anjananamika were selected. Though significant relief provided by drugs of both groups, in Lakshanas like Kandu (itching), the Rasanjantrikatu Lepa turns more effective. The primary Objective of the study was to evaluate the efficacy of Guduchi Pindi in the management of Anjananamika based on treatment outcome related to swelling, pain, burning sensation, itching and pricking sensation and thereafter, to re-evaluate the efficacy of Nimbadi Pindi in the management of Anjananamika based on treatment outcome related to swelling, pain, burning sensation, itching and pricking sensation. The secondary objective of the study was to compare the efficacy of Guduchi Pindi with that of Nimbadi Pindi in the management Anjananamika. Conclusion: In the present study no adverse drug reaction was reported thus no rescue medications were given. Guduchi has Rakta and Pittahara properties, and is also present in the Daha Prashamana Gana, due to which it may have reduced Daha. Kandu may have reduced due to its Kandughna and Tridoshahara properties, whereas Toda and Ruja may have reduced by its Ushna Veerya and Tridoshahara properties. Swelling may have reduced by the Tridoshahara, Krimihara properties of Guduchi.

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CASE REPORT

Pritika Dutta, Dipanjan Dev

Effect of Neurotherapy on Subclinical Hypothyroidism: A Case Report

[Year:2024] [Month:January] [Volume:5] [Number:1] [Pages:4] [Pages No:14 - 17]

Keywords: Subclinical hypothyroidism, overt hypothyroidism, thyroid stimulating hormone, neurotherapy

   DOI: 10.38205/imcr.050114  |  Open Access |  How to cite  | 

Abstract

The biochemical definition of subclinical hypothyroidism (SH) is an elevation of serum Thyroid stimulating hormone (TSH) or thyrotropin level with the associated triioditroponin (T3) and thyroxine (T4) levels in normal reference range. If not prevented at the initial phase, SH eventually progresses into overt hypothyroidism thereby taking a massive toll on the human health. With the advancement of alternative science over the recent decades, a novel pain-free approach has been discussed that successfully treats SH within a span of two months. In this case study, a 23-year old woman reports severe fatigue, mild mood swings and constipation. Physical examination denotes no enlargement of the thyroid gland. However, laboratory results report an elevated serum TSH of 9.85 μIU/mL (reference range: 0.39-6.16 μIU/mL) with normal free T3 (1.79 ng/ml, reference range: 0.52-1.85 ng/ml) and T4(10.17 μIU/mL, reference range: 4.6-11.2 μIU/mL) levels. To prevent the progression of the condition, “Neurotherapy” treatment is provided to the patient. The study sought to determine whether this unique treatment was effective for a patient with SH. Post therapy, laboratory results show a significant reduction of the serum TSH with no associated side-effects, thereby confirming the effectiveness of neurotherapy treatment for the prevention and further progression of this condition.

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CASE REPORT

SK. Samim Parvez, Sourita Das, Shuvasree Bhattacharya, Pratima Pramanik, Avirup Basu, SK Swaif Ali, Debojyoti Singha, Saptarshi Choudhury, Pritam Goswami

Plausible role of homoeopathic intervention in the management of Tinea Faciei; A case series

[Year:2024] [Month:January] [Volume:5] [Number:1] [Pages:13] [Pages No:18 - 30]

Keywords: Dermatophytosis, Individualized Homeopathy, Tinea faciei, Natrum muriaticum, Nux vomica

   DOI: 10.38205/imcr.050118  |  Open Access |  How to cite  | 

Abstract

Around the globe, dermatophyte infections are an increasingly prevalent type of superficial fungal infection. Several dermatophytes have a varying global distribution, where few are confined themselves to a region in particular. The nosological name of superficial dermatophyte infection varies according the location of the body, but in particular the variant that affects skin of the face is known as tinea faciei. It is frequently clinically misdiagnosed due to its variable appearance. The lancet reported it as an epidemic of fungal infection and nowadays occurrence has been fairly common OPDs and in clinical practice. Despite of being common in occurrence dermatophytosis is still a neglected topic in medical research. Different level of evidences like caser-report, case-series and RCT has been published on dermatophytosis but till date no evidence has been reported on tinea faciei only. Apart from quality of life tinea faciei has a significant impact as it can cause cosmetic disfigurement due to it's site. Here we are reporting about five cases of tinea faciei which has been managed efficiently with the help of individualized homeopathic medicine. Natrum muriaticum and Nux vomica was commonly indicated in the cases what we have treated. In all the cases significant improvement was seen without any further complications. In three out of five cases the patient was previously treated with anti-fungal combinations without much benefit, which depicts why homeopathy should be considered in the possible integration in the treatment of such fungal diseases. Though we couldn't specify the strains because of not having proper infrastructure but that is not essential for the successful homeopathic prescription. In future more structure and well designed clinical trial is desired to understand the scope and limitations for better clinical application.

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CASE REPORT

Sunil Verma, Anil Kumar Tiwari, Kapil Das

Homoeopathic Treatment of Adenomyosis: A Case Report

[Year:2024] [Month:January] [Volume:5] [Number:1] [Pages:4] [Pages No:31 - 34]

Keywords: Adenomyosis, Homoeopathy, Individualisation, Staphysagria

   DOI: 10.38205/imcr.050131  |  Open Access |  How to cite  | 

Abstract

Adenomyosis is a medical disorder where ingrowth of the endometrial tissue occurs, directly into the myometrium, resulting in uterine thickness. Clinical features of adenomyosis commonly includes menorrhagia and dysmenorrhea. The only definitive treatment for adenomyosis is a hysterectomy. This invasive procedure can avoidable with homoeopathic treatment. A 45-year-old female suffering from Adenomyosis with radiological evidence is presented here. Clinically patient reported with complaining of pain in lower abdomen and heavy painful menstrual bleeding for 2 years. After a thorough clinical evaluation, a constitutional homoeopathic medicine, i. e., Staphysagria was prescribed in increasing potency (up to Q10), when needed. Follow up assessment was done and a complete resolution of her presenting complaints was noted at the completion of the treatment. This case report proposes homoeopathic treatment as a feasible complementary or alternative therapy and emphasises the importance of repertorization in individualised homoeopathic prescription.

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CASE REPORT

Niharika Jain, Neeta Jain, Amit Kumar Jain, Simran Singh

A challenging case of pyrexia of unknown origin: the consequences of homeopathy intervention

[Year:2024] [Month:January] [Volume:5] [Number:1] [Pages:4] [Pages No:35 - 38]

Keywords: PUO, Homeopathy, Case report, Evaluation, Diagnosis

   DOI: 10.38205/imcr.050135  |  Open Access |  How to cite  | 

Abstract

Pyrexia is the most common symptom that is presented by a disease. It is of the utmost significance to diagnose the cause of a fever. An inaccurate or delayed diagnosis can pose significant risks to the patient's health. In this article, we present a 32-year-old male with a continuous fever, loss of appetite, and other constitutional symptoms. Every month, between the fifteenth and twentieth days, fever occurs. The diagnosis remained elusive despite numerous investigations. It is also important to understand the different presentations of fevers. For a successful diagnosis, it is critical to take a thorough medical history, identify the fever pattern, perform a systemic examination, and evaluate the patient through proper investigations. The report also discusses different homeopathic remedies that can help with the treatment of such fevers. In cases of PUO, it is best to start with a symptomatic approach to identify the most similar remedy.

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REVIEW ARTICLE

Muskan Kapoor, Elanchezhiyan Devarajan

The effect of yoga on hypertension: a research review

[Year:2024] [Month:January] [Volume:5] [Number:1] [Pages:7] [Pages No:39 - 45]

Keywords: Yoga, Yogic Postures, Asana, Pranayama (Breathing Practices), Meditation, Blood Pressure, Hypertension

   DOI: 10.38205/imcr.050139  |  Open Access |  How to cite  | 

Abstract

Background: Hypertension is a common condition in which the long-term force of the blood against the artery walls is high enough that it may eventually cause health problems. Uncontrolled hypertension (HTN) is responsible for 62% of cerebrovascular diseases and 45% of ischemic heart disease events. Yoga therapy may have a role in lowering blood pressure. This systematic review aims to synthesize the available literature for the same. Summary: This research review was conducted on the articles published up to January 2022. The authors searched online databases like Medline/PubMed, Science Direct, Embase, PsycINFO, Cochrane Library, and Google Scholar published in English, using Yoga for hypertension (including meditation) as the intervention and having an adequate description of the intervention. The majority of studies showed that there is a significant decrease in systolic and diastolic blood pressure. This modest decrease may significantly decrease stroke mortality and coronary heart disease in the general population. The yoga intervention included breathing exercises, meditation, and postures. Key messages: Yoga can be preliminarily recommended as an effective intervention for reducing blood pressure. This review provides an idea of the role of Yoga in hypertension and its future therapeutic implications. Additional rigorous controlled trials are warranted to investigate Yoga's potential benefits further.

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JOURNAL CLUB

Vinod Mishra

Exercise reprograms the inflammatory landscape of multiple stem cell compartments during mammalian aging

[Year:2024] [Month:January] [Volume:5] [Number:1] [Pages:3] [Pages No:46 - 48]

Keywords: Exercise, Stem cells, Ageing single cell analyses

   DOI: 10.38205/imcr.050146  |  Open Access |  How to cite  | 

Abstract

Engaging in exercise has the remarkable capacity to revitalize stem cells and enhance tissue revitalization in aging mice. This research delved into the cellular and molecular alterations occurring in a range of stem cell varieties post-exercise. It involved the elderly and young mice with aerobic exercise and analysing their stem cells at the transcriptomic level. The study demonstrated that exercise mitigates the heightened inflammation associated with aging while enhancing communication between cells, particularly via immune cells. Furthermore, it exerts a significant influence on the composition and gene expression of immune cells in both the bloodstream and tissues. In summary, this investigation provides a comprehensive insight into how exercise affects various types of aging stem cells and their surrounding environments.

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