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VOLUME 4 , ISSUE 2 ( July, 2023 ) > List of Articles

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Bone marrow mesenchymal stem cells and exercise restore motor function following spinal cord injury by activating PI3K/AKT/mTOR pathway. Neural Regen Res. 2023 May;18(5)1067–1075

Diksha Gakhar

Citation Information : Gakhar D. Bone marrow mesenchymal stem cells and exercise restore motor function following spinal cord injury by activating PI3K/AKT/mTOR pathway. Neural Regen Res. 2023 May;18(5)1067–1075. Integr Med Case Rep 2023; 4 (2):77-79.

DOI: 10.38205/imcr.040277

License: CC BY-NC 4.0

Published Online: 15-06-2024

Copyright Statement:  Copyright © 2023; Swami Paramhansa Swastha Siksha Evam Paryavaran Sanrakshan Samiti


Abstract

Despite the fact that a number of therapeutic modalities have shown promise in the treatment of spinal cord injury (SCI), focusing solely on one aspect of recovery will not lead to successful and useful regeneration in people. The current study targets an integrated approach of neuroprotection and rehabilitation strategies to treat spinal cord injury, increasing nerve regeneration and functional recovery through functional sensorimotor training and cell transplantation. Sun et al., 2022 investigated the synergistic effect of exercise training and bone marrow mesenchymal stem cell transplantation which could promote active recovery in a mice model of thoracic contusive spinal cord injury.

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